- 90% of lymphomas
- Many different types (B & T cell)
- Originates in lymph tissue
- Significant variability in how aggressive they may be|
- Hx hiv + confers markedly increased risk aggressive NHL
- Immunosupression after organ transplant→ increased risk NHL
- EBV→ Burkitts in Africa
- H pylori→ stomach MALT
- Fatigue
- Weight loss
- Diarrhea
- Other symptoms based on organ system involved
- Progressive, painless, generalized adenopathy
- Extra-nodal disease can involve almost any organ system