Decreased clearance of prolactin secondary to CKD, cirrhosis
Neurogenic: nipple stimulation, chest wall trauma
Risk Factors
Women: age 20-50, premenopausal
Symptoms
Galatorrhea
Irregular periods
Infertility (male and female
Headache, visual changes (bi-temporal heminaposia) from pressure on optic chiasm w/large macroadnoma
Men tend to present without galactorrhea and thus more advanced disease (i.e. no early warning): low testosterone→ decreased libido, erectile dysfunction, other hypogonadal symptoms
Physical Exam Findings
Galactorrhea w/o mass
Sometimes bitemporal visual field cuts (if macroadenoma compressing chiasm)