Diffuse Large Cell Lymphoma

Etiology

  • 30% of NHL

Risk Factors

  • Average age 65

Symptoms

  • Fever
  • Chills
  • Sweat
  • Adenopathy in chest, abd, pelvis, periphery
  • Can also affect GI tract, bone marrow & other extra-nodal tissues
  • Intravascular lymphoma (rare) can have systemic sx, but no findings (dx by random skin bx)
  • Overall, tends to be aggressive, w/rapid development of symptoms and findings

Physical Exam Findings

  • Adenopathy
  • Sometimes splenomegaly