Autoimmune Encephalitis

Etiology

  • Antibody mediated→ multiple including anti-nmda
  • Also paraneoplastic

Risk Factors

  • Women
  • < 30
  • Teratoma, which may be unknown at time of presentation w/encephalitis)

Symptoms

  • Agitation
  • Sub-acute, progressive changes in personality and decline in functional status (usually over weeks; sometimes months)
  • Symptoms can wax and wane
  • Confusion, bizarre behavior
  • Autonomic instability
  • Seizures, unusual movements
  • Other neurologic deficits

Tests