- Occurs secondary to an underlying problem - DM, vasculitis (e.g. PAN), RA, sarcoid, other
- Affects at least 2 distinct, non-continuous peripheral nerves, either simultaneous or serially
- Motor and sensory symptoms
- Peripheral nerve dysfunction affecting 2 or more non-contiguous nerves (e.g. peroneal and radial nerve)
- Can cause both motor (weakness) and sensory (pain/numbness) symptoms