Adult T-cell Lymphoma/leukemia

Risk Factors

  • Vertically
  • Via transfusion
  • Associated with HTLV-1→ spread sexually
  • Most prevalent in Caribbean, Central/South America, Japan

Symptoms

  • Fever
  • Chills
  • Sweats
  • Weight loss
  • Can be acute or chronic/smoldering;
  • HTLV Sx/PE→ lower extreme weakness, gait problems, incontinence, neruopathic pain

Physical Exam Findings

  • HTLV assoc findings: lower extrem weakness, spasticity, hyper-reflexia, gait problems