Whipple's Disease (T Whipplei)

Your Path

  • Whipple's Disease (T Whipplei)

Etiology

  • Rare disorder secondary to infection w/T. whipplei
  • Possibly sewage, fecal oral spread

Risk Factors

  • Male>female, age 40-60

Symptoms

  • F, adenopathy
  • Rare d/o w/multiple chronic sx
  • Wt loss, diarrhea, abd pain, fatigue
  • Intermitent migratory arthritis that sometimes precedes GI sx x years, involves larger joints→ knees, wrists, ankles
  • Broad range neuro sx→ cog impairment, uveitis, ha, supranuclear ophthalmoplegia, other
  • Also skin, cardiac, pulmonary

Tests