Erythema Multiforme (e Multiforme)

Your Path

  • Erythema Multiforme (e multiforme)


  • Infections (most common precipitants): viral→ HSV, hepatitis, EBV; bacterial→ mycoplasma, staph; fungal→ cocci
  • Allergic reaction to meds
  • Auto-immune d/o, idiopathic


  • Acute, erythematous, roundish, macules, often bullus/different colored center→ targetoid
  • Fixed in appearance x~1w
  • Usually self limited
  • Can be viewed as part of the early SJS spectrum

Physical Exam Findings

  • Erythematous eruption
  • Often w/central clearing
  • Can sometimes have bullae
  • Can have mucosal involvement