- Infections (most common precipitants): viral→ HSV, hepatitis, EBV; bacterial→ mycoplasma, staph; fungal→ cocci
- Allergic reaction to meds
- Auto-immune d/o, idiopathic
- Acute, erythematous, roundish, macules, often bullus/different colored center→ targetoid
- Fixed in appearance x~1w
- Usually self limited
- Can be viewed as part of the early SJS spectrum
- Erythematous eruption
- Often w/central clearing
- Can sometimes have bullae
- Can have mucosal involvement