- Virus spread by Aedes Aegytpi mosquito, South and Central America, Africa, Carribean
- Incubation 3d-2w
- Fever, conjunctivitis, arhthralgias of hands/feet, ha, rash, myalgia
- Symptoms typically resolve in few days
- Severe sx rare; 80% are asx
- Major concern relates to infection during pregnancy→ CNS teratogen→ microcephaly, other
- Maculo-papular rash
- Non-purulent conjunctivitis