- Age onset childhood to adult
- Travels w/autoimmune dz→ DM1, thyroid d/o, Sjogrens, IgA nephropathy, other
- Chronic abdominal bloating/distention, gas, diarrhea (GI symptoms predominate)
- Wt loss/inability to gain weight
- Fatigue from anemia (20-30%)
- Joint pain (20-30%
- Easy fractures from osteoporosis(10-50%)
- Pruritic papulo-vessicular skin eruption→ dermatitis herpetiformis (4-20%)
- Painful neuropathy (up to 30%)
- Papulo-vessicular eruption on arms (predilection for extensor surfaces), scalp, knees, back, buttocks (dermatitis herpetiformis)
- Impaired sensation and pain from peripheral neuropathy
- Serum TTG-IgA level, total IgA (r/o IgA deficiency) - drawn while consuming gluten
- CBC and iron studies; other labs to assess for other causes