- Typically pituitary tumor
- Fatigue
- Weakness
- Joint pain
- Headache
- Infertility
- Menstrual irreg
- Increase in hat or shoe size as an adult
- Increased height
- Sweating & body odor
- Visual loss afffecting temporal fields
- Characteristic appearance of face w/prominent brow and jaw
- Increasing shoe size
- Enlarging tongue
- Increased space between teeth
- Elevated IGF-1 levels
- Followed by MRI to identify pituitary abnormality