- Spread via sexual contact
- Needle sticks in health care workers
- Unscreened blood transfusion
- ~5% of acute infxn become chronic
- Long term risk cirrhosis and HCC
- Many are asymptomatic
- Acute infxn can cause N, V, malaise, jaundice, RUQ pain
- Typically self limited, resolving 2-3m
- A small group develop symmetric inflammatory arthritis MCPs, PIPs, knees ankles that resolves in few weeks
- Acute findings can include jaundice
- Symmetric inflammatory arthritis MCPs, PIPs, knees, ankles