Acute Tubular Necrosis (ATN)

Etiology

  • Acute tubular necrosis can result from: hypotension/hypoperfusion; Contrast nephropathy; myoglobin induced injury from rhabdomyolysis; other toxins
  • Often the result of multiple contributors
  • ATN is a common cause of AKI in hospitalized patients: related to co-morbidities, frequency of hypo perfusion syndromes, exposure to IV contrast agents

Risk Factors

  • Pre-existing chronic renal disease from DM, HTN, other

Symptoms

  • Fatigue
  • Edema/general volume overload
  • Diminished or absent urine output in acute phase
  • Symptoms related to the primary process (if there is one) causing hypo-perfusion

Sub-Diseases

Tests