- Acetaminophen toxicity
- Drug induced liver injury
- Acute Budd-Chiari (hepatic vein thrombosis)
- Sepsis with impaired perfusion
- Acute Wilson's disease
- Acute viral hepatitis (A, B, E)
- Autoimmune hepatitis
- Infiltrative disease from cancer
- Toxin exposure (e.g. mushrooms, drugs of abuse, other)
- Tachycardia, hypotension, signs of severe illness
- Confusion, lethargy