- Non-hodgkins lymphoma and tends to be aggressive
- Headache
- Weight loss
- Confusion
- Focal deficits
- Seizures
- Sob, cough, DOE
- Abd discomfort
- Fevers and sweats
- Eating/swallowing or digestive issues
- Other sx related to site of involvement
- Organomegaly based on site of involvement
- Focal neuro deficits
- Lung findings--> parenchymal or plerual