- Anywhere in GI tract, in particular small bowel and colon
- Associated w/RFs below
- Thin walled, dilated blood vessels that easily bleed
- Precise pathophys that leads to development unclear
- Von Willebrand's dz
- Left ventricular assist devices (LVADs), Aortic stenosis--> associated with acquired von Willebrand's dz
- Bleeding is intermittent
- Not always identifiable on endoscopy