Polycystic Kidney Disease (PCKD)

Your Path

  • Polycystic Kidney Disease (PCKD)


  • Autosomal dominant disorder leading to bilateral cysts that impair function
  • Can also causes cysts in pancreas, liver, seminal vessicles
  • Also an autosomal recessive variant

Risk Factors

  • Family history


  • Renal colic
  • Recurrent UTIs
  • Flank pain, hemturia
  • Can be asymptomatic, identified by imaging for other reasons or as part of evaluation for decline in GFR
  • Often leads to need for renal replacement therapy - though course can be variable
  • Increased risk sub-arachnoid aneurysms

Physical Exam Findings

  • Hypertension
  • Sometimes bilateral renal masses