- A family of epithelial cancers affecting nasal mucosa, pharynx, and mouth
- Keratinized squamous cell, non-keratinized, undifferentiated
- Relatively uncommon in US, more common in Asia
- Past EBV infection
- Smoking, ETOH, HPV
- Unilateral nasal obstruction, sinus area pain
- Recurrent rhino-sinusitis, otitis media, ear fullness, decreased hearing
- Non-healing ulcers/sores of nasopharynx
- Sometimes ulcer or mass visible on inspection oral cavity/posterior pharynx, nasal passageways