Your Path

  • Plasmacytoma


  • A collection of monoclonal plasma cells
  • Can occur as isolated bone lesions (typically axial skeleton) or extramedullary (typically head/neck area, in particular nasopharynx and nasal cavity)
  • Can occur concurrent w/Multiple Myeloma (in which case CRAB features present) or separately

Risk Factors

  • Age 50-60


  • Development of palpable mass(es)
  • Pain (e.g. boney, pathologic fx) or organ dysfunction based on location of plasmacytoma
  • Fatigue, sob, pain if occur in conjunction w/myeloma

Physical Exam Findings

  • Masses tend to be hard
  • Can be multiple, boney or in soft tissue