Opioid Toxidrome

Etiology

  • Intentional or unintentional overdose
  • Can be oral (many pill and liquid forms), injected (e.g. heroin, fentanyl), or inhaled (weaponized)

Risk Factors

  • Prior overdose
  • History of substance abuse

Symptoms

  • Depressed level of consciousness, confusion
  • May occur w/co-ingestions (e.g. cocaine, stimulants), that can cause other effects

Physical Exam Findings

  • Small pupils
  • Confusion, depressed level of consciousness, diminished response to stimuli
  • Low respiratory rate (or absence of breathing altogether), bradycardia, hypotension (these vary w/severity)
  • Decreased bowel sounds

Sub-Diseases

Treatments

Tests