Vitamin C Deficiency (Scurvy)

Your Path

  • Vitamin C Deficiency (Scurvy)

Etiology

  • Gastric bypass surgery
  • Extreme diets and/or lack of access to foods (typically fruits) containing vitamin C

Risk Factors

  • Following gastric bypass surgery, with impaired absorption of multiple nutrients, most commonly: iron, B12, calcium, vitamin D; less commonly thiamine (B1), zinc and copper, extreme diets
  • Extreme lack of access to foods
  • Extreme lack of interest in healthy diet (e.g. substance abuse)

Symptoms

  • Fatigue
  • Generalized weakness from myopathy and anemia (impaired iron absorption, hypo proliferative)
  • Recurrent falls (from weakness)
  • Orthostatic dizziness (lack of vitamin C impairs synthesis of catecholamines)
  • Easy bruising, tooth loss from gingival disease (impaired collagen building, capillary fragility)
  • Impaired wound healing
  • Cognitive impairment, disturbed mood

Physical Exam Findings

  • Muscle weakness
  • Persistently positive orthostatic vital signs
  • Tooth loss, gingival bleeding
  • Echymoses, easy bruising, petechiae
  • Slow to heal wounds

Tests