- Meds that cause depressed sensorium: opiates, benzodiazepines, other
- Drugs (lllicit, prescribed, overdoses) that affect cardiac function/promote dysrhythmias: tricyclics, cocaine/stimulants, other
- Other toxins: ETOH (overdose w/respiratory depression)
- Combinations of ingestions (prescribed or illicit), coupled w/other medical conditions (e.g. renal failure) that impair clearance