Other systemic disease that cause nephropathy include: multiple myeloma, HIV, hepatitis B
Risk Factors
For HV and Hep B: MSM, IVDU, sex w/prostitutes, sex without barrier protection with persons known to have HIV/Hep B or high risk; vertical spread for Hep B; unvaccinated state for Hep B
For myeloma: age > 50, MGUS
Symptoms
Fatigue, edema, SOB from nephropathy
Symptoms from HIV (based on level of disease) or Hep B (ie related to cirrhosis)
Bone pain, fatigue, weight loss, systemically feeling poorly with myeloma
Physical Exam Findings
Edema
Many findings associated w/advanced HIV
Findings of advanced liver disease w/Hep B (icterus, jaundice, spiders, ascites)
Tests
HIV Ab, HIV VL
Hep B + Sag, + Hep B VL
Myeloma: + SPEP, plasma free hight chains; often elevated Ca2+, creatinine, Total Protein