Myocarditis| Medications

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  • Myocarditis| Medications

Etiology

  • Can be direct toxic effect
  • Also immune mediated effects from check-point inhibitors (e.g. from PD-1 inhibitors)

Symptoms

  • SOB
  • Chest pain
  • Syncope/pre-syncope (dysrhythmias)
  • Key to diagnosis is linking onset of symptoms to use of medications known to cause myocarditis

Physical Exam Findings

  • Can be normal
  • Can have findings related to primary disease (e.g. lung cancer if treated w/PD-1 inhibitor)
  • Can have findings of CHF (e.g. elevated JVP, pulmonary edema, peripheral edema) - though EF can be preserved

Tests