- Can be direct toxic effect
- Also immune mediated effects from check-point inhibitors (e.g. from PD-1 inhibitors)
- Syncope/pre-syncope (dysrhythmias)
- Key to diagnosis is linking onset of symptoms to use of medications known to cause myocarditis
- Can have findings related to primary disease (e.g. lung cancer if treated w/PD-1 inhibitor)
- Can have findings of CHF (e.g. elevated JVP, pulmonary edema, peripheral edema) - though EF can be preserved
- EKG, Echo, troponins
- Exclude other causes (e.g. CAD)
- Increasingly MRI