- Associated with ? oils, impurities or other elements within vaped products
- Precise etiology as yet unclear
- Most are associated w/vaping CBD products (80+%), though can happen w/nicotine products
- Most vape qd, though RF is vaping within past 3m
- Most are young (the population who vape), with no underlying lung disease or other sig medical hx
- Acute cough, sob, fever
- 80% will have GI sx (N, V, diarrhea)
- Can progress rapidly; 1/3 of those admitted got intubated
- Very similar to other presentations for acute lung infection (e.g. community acquired pneumonia, influenza)
- Can have have fever, tachycardia, tachypnea, low O2 sat (severity varies)
- Often bilateral focal lung findings suggestive consolidation
- Supportive care, broad spectrum abx (to cover bacteria), steroids
- EVALI is a diagnosis of exclusion
- CXR, CT (often to better characterize) - typically bilateral involvement
- Labs to assess for bacterial pneumonia, influenza, r/o other processes
- Also consider hypersensitivity pneumonitis, COP, eosinophilic pneumonia, other