- Some medications can induce antibodies to react against RBCs: include cephalosporins, penicillins, check-point inhibitors, others
- Some medications induce hemolysis in setting of G6PD deficiency, including: rasburicase, dapsone, others
- G6PD deficiency - more common in people from (or with ancestral ties to) Mediterranean, Asia, Africa, Middle East
- SOB, fatigue, palpitations
- Abrupt decrease in RBCs that's otherwise unexplained
- Elevated bilirubin, reticulocyte count, LDH
- Decrease in haptoglobin