Anemia Of Chronic Inflammation (Disease)

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  • Anemia of Chronic Inflammation (Disease)


  • A common cause of hypoproliferative anemia
  • Impaired ability to absorb and export iron into plasma; also decreased RBC lifespan
  • Related to a wide array of inflammatory states including: autoimmune disorders (e.g. rheumatoid arthritis, lupus, IBD, other), chronic infections (TB, HIV, other), cancer (e.g. lymphoma, other); chronic diseases such as: cirrhosis, CKD, COPD, heart failure, cystic fibrosis, other
  • Can be chronic or acute (e.g. can develop w/in a week of critical illness w/severe infection)
  • Diagnosis based on having a chronic inflammatory state and no other identified contributors