- Problem at level of adrenal gland, including: autoimmune destruction → assoc w/dm 1, celiac dz
- Adrenal hemorrhage/infarct
- Adrenal infection → TB, HIV
- Adrenal infiltration w/tumor
- Meds (e.g. Ketoconazole)
- Sub-acute feeling poorly in general, fatigue, weakness
- Abdominal pain, nausea, vomiting
- Weight loss, muscle aches
- Orthostatic sx/dizziness
- Decreased libido in women
- Hypotension: frankly low BP and/or orthostatic
- Loss of axillary & pubic hair in women
- Sometimes darkening of mucous membranes, skin folds, & pressure points
- Low cortisol, elevated ACTH
- Other suggestive labs: hyponatremia and hyperkalemia; mild eosinophilia; sometimes hypoglycemia