Drug induced→ hydralazine, procainamide, INH, others
Risk Factors
Female > Male
Black>White
Age onset 15-50
Symptoms
Sub-acute onset
Photosensitive
Rash on face
Fever and feeling poorly in general
Discoid eruption on body
Multi-system involvement including: CNS: confusion, seizures; kidney involvement; muscle aches, pain; inflammation of 2 or more peripheral joints→ can be migratory
SOB w/pleural, parenchymal, or pulmonary vascular (pulmonary htn) disease
CP if pericarditis
Weakness, numbness, or neuropathic pain w/PNS involvement (rare)
High risk atherosclerosis (MI, stroke)
Physical Exam Findings
Pericardial rub
Adenopathy
Painless oral ulcers
Malar and nasal bridge erruption sparing naso-labial folds
Discoid erruption on body
Pleural rub or findings of effusion
Inflammatory arthritis
Scarring hair loss
Elevated JVP, edema, loud P2, other findings of plum htn