- Autoimmune w/ab targeting ACh receptor
- 10% will have thymoma
- Worse w/repetitive movement, end of day
- Ocular form: double vision, drooping eyelids, other cranial nerve palsies; may fluctuate
- Generalized form: systemic weakness affecting neck, extremities, other muscles→ asymmetric and prox > distal fashion
- Reflexes preserved
- No sensory findings
- Ptosis (eyelid covering at least part of pupil)
- Eye muscle weakness
- Other CN palsies
- Weakness in other muscles→ worse w/use
- Can cause systemic weakness affecting neck, extremities, other muscles→ asymmetric, prox > distal