Histoplasmosis

Sites

  • Lungs
  • Liver
  • Spleen
  • Eye
  • Mouth
  • Systemic

Etiology

  • Fungus

Risk Factors

  • Mississippi & Ohio river valley
  • Exposure to bird or bat droppings→ chicken coops/caves
  • HIV+, otherwise immunocomp

Symptoms

  • Incubation 1-4w
  • Cough
  • Fever
  • Flu-like
  • Can be asx/mild and resolve spont; often see x-ray evidence prior infection lung, spleen w/o known past infxn
  • Tends to cause resp/systemic illness, oral ulcers in HIV+ or immunocomp

Physical Exam Findings

  • Normal hosts usually dont have manifestations
  • HIV + can affect most organ systems: oral ulcers, hepatomegaly, splenomegaly, skin, adenopathy, focal lung findings, other

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