- Skin (cellulitis), soft tissue abscess, wound, joints, valves, bacteremia, bones w/osteo, toxin mediated illnesses, other
- MRSA or MRSA, either of which can be acquired in the hospital or community
- Typically via break/compromise of skin often portal of entry
- Can occur in anyone, though more susceptible if compromised host (e.g. diabetes, vascular disease, injection drug use, etc)
- Skin: cellulitis alone is more typically strep; purulence/abscess suggests staph
- Osteomyelitis via direct extension
- Arthritis: enters joint via hematogenous spread or direct inoculation
- Bacteremia, with seeding of abnormal or artificial valves, joints or devices; virulent w/rapid destruction valves/death w/in hours/days
- Toxic shock: fever, confusion, severe illness
- Scalded skin (toxin mediated): fever, severe illness, painful erythema and desquamation
- Pneumonia: (post viral or intubated) cough, sputum, sob; can be rapid and necrotizing, leading to lung abscess and severe illness
- Toxin based food poisoning→ n/v hours after exposure, others affected who ate same
- Cellulitis→ redness, warmth, induration, skin abscess→ focal redness and fluctuance
- Inflammation over/within infected structure
- Systemic illness w/bacteremia
- Other findings based on site and mechanism (e.g. pneumonia, toxins, etc)