Mycobacterial - MAC

Sites

  • Lungs in non-HIV+
  • HIV+: lungs, lymph nodes, bone marrow, anywhere in GI tract, systemic

Risk Factors

  • Cystic fibrosis
  • HIV +→ CD4 < 50
  • Bronchietasis→ assoc w/copd
  • Prior lung infxns

Symptoms

  • HIV-: acute lung infxn assoc w/persistent & progressive cough, sob, sputum; infxns tend to recur
  • HIV+: sob, cough, diarrhea, n, v, abdominal pain, f, c, fatigue, adenopathy

Physical Exam Findings

  • HIV-: focal lung findings, wheezing, other
  • HIV +: can infect any organ system including liver, spleen, lymph nodes, bone marrow, lung, pericardium, adenopathy, organomegaly, anemia, other