Alpha 1 Anti-trypsin Deficiency

Etiology

  • Genetic d/o that leads to lung destruction and liver dysfxn

Risk Factors

  • Age 30-40, family hx

Symptoms

  • Sob
  • Progressive doe
  • Episodic exacerbations
  • Similar to COPD but no/limited smoking hx
  • Chronic progressive liver dz

Physical Exam Findings

  • Wheezing
  • Signs chronic liver dz