- Localized areas subcu swelling
- Response to a precipitant, including: meds (e.g. NSAIDs, Opiates), IV contrast, food, latex, insect bite/stings, other environmental triggers
- Itching
- Flushing
- Abd pain
- Can be severe and life threatening due to airway issues
- Can occur w/anaphylactic rxns→ low bp w/systemic sx
- Swelling of face & other body parts
- Edema often asymmetric and non-pitting