- Skin, lungs, GI tract, liver, other
- KS development is related to the presence of Human Herpesvirus-8 (HHV 8)
- More common in men who have sex w/men, due to higher prevalence HHV 8 in this group
- Can also occur in elderly (non-HIV related)
- Progressive skin nodules on skin
- Other symptoms related to dysfunction in organ system(s) that are affected
- Purplish/red/brown nodules, occur anywhere on skin