- Most commonly from Hashimoto's
- Constipation
- Weakness
- Fatigue
- Cold intolerance
- Depression/mood change
- Myxedema coma very rare
- Often no findings aside from wt gain
- Sometimes decreased relaxation phase of reflexes
- Pre-tibial edema or generalized fluid retention
- Lateral thinning of eyebrows
- Sometimes goiter, though usually no palpable findings
- Elevated TSH
- Decreased T4 and T3