- Inappropriate secretion of epi/norepi from adrenal medulla (rare condition)
- Genetic predisposition
- Associated w/MEN2 (rare): medullary thyroid cancer, hyper-parathyroidism and pheochromocytoma
- Assoc w/findings related to abrupt, paroxysmal increase in sympathetic d/c--> headache, sweating, sense of pounding heart rate
- Fatigue following episodes
- Rarely causes cardiomyopathy
- Elevated heart rate and blood pressure
- 24h urine collection: fractionated metanephrine, normetanephrine
- Plasma fractionated metanephrine, normetanephrine
- Imaging to localize: CT or MRI