Aspirin Toxicity

Etiology

  • Caused by unintentional over treatment for pain or suicide attempt
  • Causes metabolic acidosis and respiratory alkalosis (primary via CNS stimulation)

Symptoms

  • Ringing in ears
  • N
  • V
  • Abdominal pain, hematemesis
  • Range from confusion/agitation to somnolence

Physical Exam Findings

  • Tachypneic
  • Can be very ill appearing
  • Agitation/confusion, though can also be somnolent
  • Often tachycardic and febrile
  • Sometimes abdominal distention
  • Sometimes non-cardiogenic pulmonary edema

Tests