- Unusual neuroendocrine tumor
- Profound watery diarrhea that persists despite fasting
- Can be precipitated by choclate or alcohol intake
- Sometimes wheezing
- Sometimes tricuspid and/or pulmonary valvular abnormalities
- Elevated 24h urine 5HIAA, serum Chromogranin A
- Imaging w/CT, MRI, PET; Somatostatin scintigraphy; Can also be visualized (and bx) endoscopically