Minimal Change Glomerulopathy

Etiology

  • Acounts for 70-90% of Nephrotic syndrome in kids
  • 10-15% in adults
  • Idiopathic though assoc w/meds (lithium, nsaids), infxn (mono)
  • Malignancies (lymphoma)

Symptoms

  • Edema develops rapidly (over weeks)
  • GFR often preserved
  • Unexplained venous thrombosis

Physical Exam Findings

  • Peripheral edema
  • Sometimes periorbital and hand edema
  • HTN may be present

Tests