- Adenocarcinoma (lower 2/3): Age > 50, assoc w/GERD→ Barret's
- Squamous cell (upper 2/3): Age >50, assoc w/etoh and smoking
- Sub-acute and progressive swallowing probs more than pain
- May vomit to relieve obstruction
- Worse w/solids then liquids
- May have weight loss if advanced
- May have black stools (if significant bleeding) and guaiac +