- Ongoing ingestion of alcohol
- Often superimposed on chronic liver disease (frequently known or occult underlying cirrhosis)
- Sometimes fever
- RUQ pain
- Jaundice
- Icterus
- Confusion
- Muscle loss
- Sometimes ascites
- Often hepatomegaly, sometimes tender
- Elevated total bilirubin
- Elevated transaminases, with AST > ALT (often ratio > 2:1); values typically < ~300
- Often elevated INR, WBC (though still need to consider infection)
- Maddrey's discriminant function: 4.6 x (patient's PT - control PT) + TB; > 32 =s high risk, consideration for corticosteroids