- Obstructing gall stone at cystic duct
- Acalculous cholecystitis from stasis, often associated with severe illness in hospitalized patients
- Organisms typically GNRs, enterococcus
- Cholesterol stones: Female, age > 40, obesity, Native American
- Bilibubin stones (uncommon) from processes that cause hemolysis (e.g. sickle cell disease)
- Constant right/upper abdominal pain
- Can radiate to back, right shoulder
- Nausea, vomiting
- Palpating hand positioned below liver→ patient inspires→ pain increases when inflamed gall bladder contacts hand (Murphy's Sign)