Liver Cancer


  • Secondary to chronic hepatitis for any reason, leading to cirrhosis
  • Can also be mets to liver

Risk Factors

  • Chronic alcoholic hepatitis
  • Chronic hepatitis B, C
  • Fatty liver-->NASH
  • Hemochromatosis, Wilson's disease, other uncommon genetic disorders
  • Sometimes from multiple contributors (e.g. ETOH + Hep C)


  • Anorexia
  • Weight loss
  • Jaundice
  • Fever, sweats
  • Typically sub-acute, persistent/progressive RUQ area pain

Physical Exam Findings

  • Often firm, palpable liver
  • Sometimes jaundice