C Dif Colitis

Etiology

  • Toxin based
  • Antibiotic associated colitis

Risk Factors

  • Most commonly implicated antibiotics: clindamycin, cephalosporins, quinalones; though can occur after any abx
  • Also passed to patients in hospital via healthcare workers
  • Prior history of c dif
  • Advanced age; significant medical conditions including: cancer, renal failure, generalized debility; chemotherapy

Symptoms

  • Cramps
  • Diarrhea, at least 3x/day
  • Sometimes nausea, vomiting
  • Sometimes blood in stool
  • Severe pain and sepsis if advanced

Physical Exam Findings

  • F
  • May have generalized abd pain
  • Sometimes distention
  • With severe disease--> toxic megacolon--> very ill

Tests

Links