Infection Related GN (formerly Post Streptococcal GN)

Etiology

  • In past, linked to post-streptococcal skin or pharyngeal infxn
  • Now recognized can follow other bacterial or viral infxns
  • Most commonly in adults post-Staph

Risk Factors

  • Male > female
  • Typical age 2-10

Symptoms

  • Fatigue
  • Weakness
  • Proteinuria
  • Onset 10-14 d after infxn
  • Painless passage of dark ("coca-cola") colored urine
  • Often lab evidence decline in GFR
  • Most episodes resolve spontaneously
  • Can have confusion or even seizure from hypertensive encephalopathy

Physical Exam Findings

  • Often hypertensive
  • Dark colored urine

Tests