Idiopathic Thrombocytopenic Purpura (ITP - Destructive)

Etiology

  • Atuoimmune destruction of platelets
  • Can be primary (ie idiopathic ITP) or secondary
  • Secondary ITP related to hep c, HIV, H Pylori, SLE, Sjogrens, other autoimmune disorders

Symptoms

  • Mucocutaneous bleeding
  • May be acute or chronic

Physical Exam Findings

  • No hepato-splenomegaly or other if primary
  • If secondary→ finding of primary d/o
  • Petechiae and mucosal bleeding

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