Paroxysmal Nocturnal Hemoglobinuria (PNH)

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  • Paroxysmal nocturnal hemoglobinuria (PNH)

Paroxysmal nocturnal hemoglobinuria (PNH) Detail 🌳 View as Mindmap

Etiology

  • Unusual d/o
  • Avg age onset 30s
  • Hemolysis due to increased susceptibility to compliment

Symptoms

  • Sob
  • Doe
  • Fatigue
  • Spontaneous venous thrombosis→ portal, hepatic, mesenteric and extremity veins
  • Episodic hemolysis, in partic after infxn
  • Decreased production all cell lines