Low Systemic Vascular Resistance (SVR)

Etiology

  • Other
  • Impaired peripheral arterial tone: sepsis (bacterial most common)
  • SIRs for non-infectious reasons
  • Meds (e.g. alpha-blockers)
  • Autonomic dysfunction (e.g. DM or other neuropathy)
  • Metabolic/autoimmune (adrenal insufficiency)

Risk Factors

  • Chemo therapy (immuno-compromised)
  • Age (very young or old)
  • Underlying diseases (e.g. post-splenectomy, HIV, cancer, diabetes, etc.)
  • Meds which decrease peripheral tone or predispose to infection, other

Symptoms

  • Lightheaded, dizzy, weak, confuse
  • Cold (hypo-perfusion, hypothermia)
  • Hot/febrile (if related to sepsis)
  • Loss of consciousness
  • Sx exacerbated by moving from lying/sitting to standing→

Physical Exam Findings

  • Low BP
  • May be very ill appearing (depending on etiology)
  • May have +orthostatic vital signs
  • Depending on cause, periphery can feel warm/moist

Sub-Diseases

Other Diagnoses

Links